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and IGHV provide the strongest effect on a patient’s consequence, and it can be consequently not astonishing that simplified versions on the CLL-IPI incorporating only both of these markers are actually proposed. one hundred and one A recent review has determined that a rating according to the existence of unmutated IGHV, complete lymphocyte count >fifteen x109/L, and palpable lymph nodes predicts for a shorter time and energy to initial cure in individuals with early, asymptomatic disorder.
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